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NAFDAC faults publication on under dose paracetamol

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NAFDAC faults publication on under dose paracetamol
NAFDAC faults publication on under dose paracetamol

The National Agency for Food and Drug Administration and Control (NAFDAC), based on its scientific findings, faults claims that nearly all paracetamol drugs in the country are under the recommended doses.

Prof. Mojisola Adeyeye, the Director-General of NAFDAC, made this known on Monday while briefing newsmen on findings carried out by the agency due to a publication’s claim of under dose paracetamol tablets in the country.

Adeyeye said that based on a scientific response to recent reports suggesting widespread under dosing of paracetamol tablets in Nigeria, NAFDAC conducted a comprehensive testing of tablets, sampled from different pharmacy outlets to investigate these claims.

“As a Scientist and Professor of Pharmaceutical Manufacturing and Drug Evaluation for 30 years, the publication gave me a great concern on the lack of responsibility regarding the impact of the unscientific release on the Nigerian society.

“The results of the laboratory testing are ready after paracetamol tablets from 13 different local manufacturers were sampled from Lagos and Abuja pharmacy outlets.

“We assured the public that we will publish the result of our own investigation of the paracetamol tablets in Nigeria immediately we conclude testing in the agency’s WHO pre-qualified laboratory.

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“A minimum of 20 tablets from each manufacturer were used for the assay analysis by regulatory officers with verifiable analytical skills and competencies using the British Pharmacopoeia monograph 2023 edition Volume 3.

“The result of our test clearly showed that all the 20 tablets from each manufacturer met the stipulated dosage standards and specification.

“This includes adherence to both national and international regulatory requirements”.

She said: “This is a 100 per cent pass rate for the full compendia tests result for the 20 samples of paracetamol tablets tested.

“While the assay was validated using British Pharmacopoeia testing methodologies for precise and reliable assessments of the dosage levels in the sampled paracetamol tablets.

“The assay results clearly contradict the results of the published report circulated on social media and we fault this grim publication in totality,” she said.

She added that parameters including uniformity of mass, average weight, friability, hardness, identification and disintegration time that were not part of the subject in question were also tested.

They were found to have met the BP specifications, she said.

“Basic scientific facts such as the range of the concentrations of the standard curve solutions (0.01 to 0.05) being lower than the solution test samples (0.1) further invalidates all the analysis because the anticipated test solution concentration should fall within the calibration concentration range.

“These are basic laboratory testing and scientific facts that those competent in pharmaceutical and regulatory science should know.

” These are the simplest of many rigorous tests that earned the NAFDAC Central Drug Control Laboratory the coveted Pre-qualification by World Health Organisation (WHO),” she said.

According to Adeyeye, the pharmaceutical manufacturing sector in the country strives to maintain and enhance the quality of pharmaceutical products to align with NAFDAC’s quality culture.

“This publication that has now been retracted is a disservice to the pharmaceutical industry and the nation.

“The mischief of placing the article in the social media on the background of World Health Organisation logo is highly distasteful and illegal.

“NAFDAC emphasises the importance of evidence-based information to guide public discourse and urges stakeholders to rely on and check for accurate and comprehensive data”.

The Director-General reassured Nigerians of the agency’s commitment to public health and safety.

NAFDAC faults publication on under dose paracetamol

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Health

Only 58,000 doctors renewed licence out of 130,000 registered doctors – MDCN

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Only 58,000 doctors renewed licence out of 130,000 registered doctors — MDCN

Only 58,000 doctors renewed licence out of 130,000 registered doctors — MDCN

The Medical and Dental Council of Nigeria (MDCN) says only 58,000 doctors renewed their annual practice licence out of the 130,000 registered doctors in the country.

The Deputy Registrar of MDCN, Dr Victor Kolawole, disclosed this at the Induction/Oath Taking Ceremony of the 2022/2023 Batch B Medicine and Surgery graduates of the Edo State University, Uzairue, on Friday.

Kolawole said “since inception in 1963, we presently have over 130,000 registered doctors in Nigeria.

“However, as you know because of the increase in migration of doctors out of the country, we have about 58,000 doctors who renewed their annual practice licence in 2023 and they are those that are fit to practice in Nigeria.”

He frowned at the current sydrome of doctors going abroad for greener pasture and appealed to the newly medical graduates to stay back and practice their profession in the country.

He said that “by this induction of 20 new doctors into the health workforce, we hope that other institutions will follow suit even as the government said that the quota should be increased in all our training centres.

“However, the doctors must meet the requirements to earn those increase in quota.

“We will partner them to ensure that they met those requirements and as we try to ensure that, standard must be upheld.”

He dmonished the new medical practitioners to uphold the sanity of the profession and be law abiding, as the council is
mandated to regulate activities of practitioners as well as punish offenders.

In his welcome address, the Vice Chancellor of the institution, Prof. Emmanuel Aluyor, said the institution has facilities to train medical personnel in the country.

Aluyor thanked Gov. Godwin Obaseki “for his unwavering support to the great university and for establishing the university teaching hospital through the conversion of the Central Hospital, Auchi.

“This significant upgrade has enhanced facilities for the training of medical students and uplifted the standard of healthcare services in Edo North and its environs.

“It is noteworthy that Edo State University Teaching Hospital Auchi is the first state-owned teaching hospital in Edo.

“I respectfully urge the state government to sustain efforts toward improving facilities at Edo State University Teaching Hospital, Auchi.

Earlier, the acting Provost, College of Medical Sciences, Dr Kenneth Atoe, said 20 medical graduands from the college are the second Batch B inductees.

Atoe advised the newly qualified medical graduates to uphold the ethical standards of a medical professional.

“You must internalise the values of honesty, integrity and selflessness.

“These virtues are not only essential for building strong doctor-patient relationship, but, are also integral to upholding the ethical standards and trustworthiness expected of a medical professional.

“By embodying these values, doctors not only fulfil their professional obligations, but also contribute to the maintenance of public trust in the medical profession,”Atoe said.

Only 58,000 doctors renewed licence out of 130,000 registered doctors — MDCN

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Entertainment

Actors Guild hails Tinubu on intervention for Nollywood Actor, Zack Orji’s health

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Actors Guild hails Tinubu on intervention for Nollywood Actor, Zack Orji’s health

The Actors Guild of Nigeria (AGN) has expressed appreciation to President Bola Tinubu for his fatherly intervention on the health of Nollywood Actor, Zack Orji, who had departed to the United Kingdom for post-surgery assessment.

Dr Emeka Rollas, National President of AGN, gave the commendation in a statement on Saturday.

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Rollas also commended the First Lady, Sen. Oluremi Tinubu, for her motherly care towards the veteran actor as well as the son of the President, Seyi Tinubu, for his unflinching support.

“We have witnessed the unprecedented support that President Tinubu is giving to the creative industry.

“This has clearly shown his clear determination to uplift the sector to be more relevant and beneficial to both the practitioners and the national economy and we find it necessary to appreciate him.

“We also appreciate the Minister for Women Affair, Uju Kennedy-Ohanenye, for her relentless efforts in ensuring that Zack Orji gets back on his feet hale and hearty.

“Zack Orji equally extends his profound gratitude to his longtime friend, Ahmed Bala, for standing by him all through the period.

Actors Guild hails Tinubu on intervention for Nollywood Actor, Zack Orji’s health

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Health

Sleep deprivation affects over 700 genes in human body – Physician

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Sleep deprivation affects over 700 genes in human body – Physician

Dr Moyosore Makinde, a Consultant Family and Lifestyle Medicine Physician, says
over 700 genes in the human body can be affected when an individual fails to sleep when due.

The consultant made this known in an interview with the News Agency of Nigeria (NAN) in Lagos on Tuesday, in commemoration of
the 2024 World Sleep Day (WSD).

NAN reports that WSD is celebrated annually on March 15 to raise awareness about the significance of sleep and the ills of sleep deprivation.

The 2024 World Sleep Day has “Sleep Equity for Global Health” as its theme.

Markinde, also the President, Society of Lifestyle Medicine of Nigeria (SOLON), therefore, told NAN that sleep deprivation could have social, economic and health implications.

Also a member of the World Sleep Society, Markinde said that “sleep deprivation is usually caused by intentional human behaviour such as watching TV, viewing social media on phones, night shifts, night study, night travel and even night vigils.

“All these activities can disrupt the circadian rhythm, which is the body’s biological clock.

“Sleep helps to control the secretions from various body tissues and organs such as the growth hormone, the stress hormone and the hunger hormones.

“It also plays important roles in respiration, blood pressure and immunity.

“Sleep is so important that if an individual fails to observe when due, over 700 genes in the body can be affected.”

The physician said that sleep deprivation could also increase the risk of contracting some Non-Communicable Diseases (NCD), adding that “it is the cause of a great number of accidents on Nigerian roads too.

“And aside causing fatal vehicular accidents and judgmental errors at work, sleep insufficiency or deprivation can increase the risk of heart disease,
type 2 diabetes and some cancers, especially breast and prostate cancers.

“Some people also have certain sleep disorders which can affect their ability to sleep and they will need to be evaluated by a sleep physician.”

Markinde explained that the normal duration expected of an individual to sleep varies, based on the age of the individual.

She said that the World Health Organisation (WHO) recommended at least seven to eight hours of restorative sleep for adults above 18 years,
adding that infants and children require more hours of sleep compared to adults.

She, therefore, advised that people should make out time for sleep, rest and relax for optimal health.

“Infants require up to 16 hours of sleep, while pre-school and schoolage children need up to 13 hours and 12 hours of sleep respectively.
This is important for the development of their brains.

“Sleep is as important as the food we eat, the water we drink and the air we breath.

“It is a natural state of rest and a period dedicated to help the body repair itself physiologically and naturally.

“Amid the hustle and bustle of work, study, business and pleasure-seeking activities, Nigerians need to prioritise sleep. In so doing, we will be prioritising our health,” Markinde said.

Sleep deprivation affects over 700 genes in human body – Physician

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